• Pediatr Crit Care Me · Jul 2012

    Randomized Controlled Trial

    Effect of body position on ventilation distribution in preterm infants on continuous positive airway pressure.

    • Judith L Hough, Leanne Johnston, Sandy G Brauer, Paul G Woodgate, Trang M T Pham, and Andreas Schibler.
    • Paediatric Critical Care Research Group, Paediatric Intensive Care Unit, Mater Health Services, South Brisbane, QLD, Australia. judith. hough@mater.org.au
    • Pediatr Crit Care Me. 2012 Jul 1; 13 (4): 446-51.

    RationaleAlthough continuous positive airway pressure is used extensively in neonatal intensive care units, and despite the belief that positioning is considered vital to the maintenance of good lung ventilation, no data exist on regional ventilation distribution in infants on continuous positive airway pressure ventilatory support.ObjectivesTo investigate the effect of body position on regional ventilation in preterm infants on continuous positive airway pressure ventilatory support using electrical impedance tomography.DesignRandomized crossover study design.SettingNeonatal intensive care unit.PatientsTwenty-four preterm infants on continuous positive airway pressure were compared to six spontaneously breathing preterm infants.InterventionsRandom assignment of the order of the positions supine, prone, and quarter prone.Measurements And ResultsChanges in global and regional lung volume were measured with electrical impedance tomography. Although there were no differences between positions, regional tidal volume was increased in the posterior compared with the anterior lung (p < .01) and in the right compared with the left lung (p < .03) in both the spontaneously breathing infants and in the infants on continuous positive airway pressure. The posterior lung filled earlier than the anterior lung in the spontaneously breathing infants (p < .02), whereas in the infants on continuous positive airway pressure the right lung filled before the left lung (p < .01). There was more ventilation inhomogeneity in the infants on continuous positive airway pressure than in the healthy infants (p < .01).ConclusionsThis study presents the first results on regional ventilation distribution in preterm infants on continuous positive airway pressure using electrical impedance tomography. Gravity had little impact on regional ventilation distribution in preterm infants on continuous positive airway pressure or in spontaneously breathing infants in the supine or prone position, indicating that ventilation distribution in preterm infants is not gravity-dependent but follows an anatomical pattern. AUSTRALIA NEW ZEALAND CLINICAL TRIALS REGISTRY:: ACTRN12606000210572.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…

What will the 'Medical Journal of You' look like?

Start your free 21 day trial now.

We guarantee your privacy. Your email address will not be shared.