• Anticancer research · May 2015

    Review

    Randomized Trials of Systemic Medically-treated Malignant Mesothelioma: A Systematic Review.

    • Carl Blomberg, Jonas Nilsson, Georg Holgersson, Per Edlund, Michael Bergqvist, Linda Adwall, Simon Ekman, Daniel Brattström, and Stefan Bergström.
    • Department of Oncology, Gävle Hospital, Gävle, Sweden Centre for Research and Development Uppsala University/County Council of Gävleborg, Uppsala, Sweden Department of Radiation Sciences and Oncology, Umeå University Hospital, Umeå, Sweden.
    • Anticancer Res. 2015 May 1;35(5):2493-501.

    AbstractMalignant pleural mesothelioma (MPM) is a rare but aggressive malignancy mainly localized to the pleura. Malignant mesothelioma grows highly invasive into surrounding tissue and has a low tendency to metastasize. The median overall survival (OS) of locally advanced or metastatic disease without treatment is 4-13 months but, during recent years, improvement in survival has been achieved since treatment for patients with mesothelioma has improved with better palliative care, systemic medical treatment, surgery and improved diagnostics methods. The present review aims at describing available data from randomized trials considering systemic medical treatment for this patient category.Copyright© 2015 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.

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