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Comparative Study Clinical Trial
Long-term follow-up in children with functional hemispherectomy for Rasmussen's encephalitis.
- R Shane Tubbs, Shahid M Nimjee, and W Jerry Oakes.
- Department of Cell Biology, University of Alabama at Birmingham, Birmingham, AL, USA. rstubbs@uab.edu
- Childs Nerv Syst. 2005 Jun 1;21(6):461-5.
IntroductionCerebral hemispherectomy has been performed for over 60 years. Multiple variations of functional hemispherectomy have been performed since its inception by Rasmussen. Long-term follow-up for these variations is lacking in the medical literature.MethodsWe review the long-term follow-up for five children with Rasmussen's encephalitis who underwent a modification of functional hemispherectomy.ResultsThe length of follow-up for this cohort ranged from 13 to 23 years (mean 15.6 years). All patients experienced immediate and complete elimination of seizures. Only one patient underwent ventriculoperitoneal shunt placement. All patients are capable of ambulating on their own. Many years following their procedures, this cohort of patients remains seizure free.
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