• Kuan-Jen Chen, Yih-Shiou Hwang, Yen-Po Chen, Chi-Chun Lai, Tun-Lu Chen, and Nan-Kai Wang.
• Department of Ophthalmology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kwei-Shan, Taoyuan, Taiwan. cgr999chiayi@yahoo.com.tw
• Ocul. Immunol. Inflamm. 2009 May 1;17(3):153-9.

PurposeTo investigate the management, bacterial strains, antibiotic sensitivities, and visual outcomes in patients with Klebsiella pneumoniae pneumonia and endogenous Klebsiella endophthalmitis.MethodsData were collected for treatments, antibiotic sensitivity patterns, and final visual outcomes.ResultsThe study included 10 eyes of 9 patients with a median age of 42 years (range, 0-86 years). Diabetes mellitus was the most common comorbid risk factor (n = 5, 56%). Nine eyes (90%) were treated with intravitreal antibiotics, and one with pars plana vitrectomy and intravitreal antibiotics. One eye achieved a favorable visual acuity of 20/20; however, 6 eyes developed vision of no light perception, including 2 of evisceration. Two nosocomial K. pneumoniae isolates were extended-spectrum-beta-lactamase-producing strains, which demonstrated the resistance to amikacin and ceftazidime.ConclusionsOphthalmologists and physicians should be aware of Klebsiella pneumonia as a possible cause of endogenous endophthalmitis, and endogenous Klebsiella endophthalmitis usually causes poor visual outcomes.

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