• Asian Cardiovasc Thorac Ann · Dec 2006

    Valved patch for ventricular septal defect with pulmonary arterial hypertension.

    • Abbas Afrasiabi, Mahmoud Samadi, and Hossein Montazergaem.
    • Cardiovascular Research Center, Madani Heart Hospital, University of Medical Sciences, Tabriz, Iran. aafrasa@yahoo.com
    • Asian Cardiovasc Thorac Ann. 2006 Dec 1;14(6):501-4.

    AbstractFrom March 1998 to December 2004, 16 acyanotic patients aged 2 to 22 years (mean, 7 +/- 5.7 years) with a large ventricular septal defect and elevated pulmonary vascular resistance (9.6 +/- 3.8 Wood units) underwent surgery. A Gore-Tex patch with a 5-8 mm longitudinal slit in the center was used. A piece of pericardium was sewn around the slit on one side of the patch, except for the upper quarter. In all patients, the defect was closed with a trimmed patch and the pericardial aspect was placed on the left ventricular side to allow right-to-left shunting. Echocardiography on the day of operation revealed a right-to-left shunt in 6 cases. Two patients (12.5%) died in the early postoperative period due to frequent episodes of pulmonary hypertensive crisis and persistent severe pulmonary hypertension. In 3 years of follow-up, pulmonary vascular resistance gradually decreased in all but one patient in whom it increased with a right-to-left shunt and cyanosis. Insertion of a valved patch seems to be a promising technique to decrease morbidity and mortality in severe pulmonary arterial hypertension.

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