• Angélica de Fátima de Assunção Braga, Franklin Sarmento da Silva Braga, Eunice Sizue Hirata, Rosa Inês Costa Pereira, José Aristeu Frias, and Isadora Fregonese Antunes.
• Department of Anesthesiology, School of Medicine, Campinas State University, Campinas, SP, Brazil.
• Acta Cir Bras. 2014 Nov 1;29(11):752-8.

PurposeTo evaluate the efficacy and side-effects of fentanyl and sufentanil combined with hyperbaric spinal bupivacaine in elective cesarean section.MethodsA prospective, randomized, double-blind study with 64 term parturients, distributed into 2 groups according to the opioid combined with hyperbaric bupivacaine 0.5% (10mg): GF - fentanyl (25 µg) and GS - sufentanil (5.0 µg). The latency and maximum sensory block level; degree and duration of motor block; duration and quality of analgesia; maternal-fetal repercussions were evaluated. This was an intention-to-treat analysis with a 5% significance level.ResultsThe latency period, maximum sensory block level, motor block degree and perioperative analgesia were similar in both groups. Motor block and analgesia had a longer duration in the sufentanil group. Maternal adverse effects and neonatal repercussions were similar. The incidence of hypotension was higher in the fentanyl group. In both groups, there was a predominance of patients who were awake and either calm or sleepy.ConclusionsThe addition of fentanyl and sufentanil to hyperbaric subarachnoid bupivacaine was shown to be effective for the performance of cesarean section, and safe for the mother and fetus. Analgesia was more prolonged with sufentanil.

37 keywords...

hide…