• E M Tarazi and B K Philip.
• Department of Anesthesia, Brigham and Women's Hospital, Boston, MA, USA.
• J Clin Anesth. 1998 Jun 1;10(4):272-7.

Study ObjectiveTo determine if there is a difference between sevoflurane and desflurane when used as part of a balanced anesthetic technique in terms of time to discharge from an ambulatory surgery unit.DesignRandomized, double blind study.SettingAmbulatory surgery unit of a large, metropolitan teaching hospital.Patients60 ASA physical status I and II adult women undergoing laparoscopic tubal ligation on an outpatient basis.InterventionsPatients were randomized to receive either sevoflurane or desflurane as a component of a balanced anesthetic technique. Visual analog scores (VAS) for discomfort, nausea, and wakefulness, and digit-symbol substitution tests (DSST) were completed preoperatively and at specified intervals after extubation.Measurements And Main ResultsTime to eye opening, command response, orientation, sitting in bed, sitting with legs dangling, standing, walking, discharge, and departure were measured for all patients. VAS and DSST scores were compared with preoperative baseline scores.ConclusionsRecovery indices and psychomotor function are marginally but not significantly better with sevoflurane than desflurane.

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