• Acta Anaesthesiol Taiwan · Sep 2010

    Case Reports

    Progressive muscle weakness with respiratory insufficiency in a young patient with tetanus during magnesium sulfate infusion.

    • Preethy Joseph Mathew, Narayanan Muthurajan, and Jyotsna Wig.
    • Department of Anaesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research, Chandigarh, India. tjpreethy@rediffmail.com
    • Acta Anaesthesiol Taiwan. 2010 Sep 1;48(3):152-4.

    AbstractMagnesium sulfate administered as an intravenous infusion is considered safe. However, there have been concerns about the neuromuscular blocking properties of magnesium that can cause respiratory insufficiency. We report a patient with mild tetanus who, after being started on magnesium infusion, developed progressive respiratory insufficiency, proximal muscle weakness and ptosis. On discontinuation of magnesium infusion, the muscular weakness improved and respiration became normal. The safety of magnesium sulfate infusion for the management of tetanus needs to be re-evaluated.Copyright © 2010 Taiwan Society of Anesthesiologists. Published by Elsevier B.V. All rights reserved.

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