• Methods Mol. Biol. · Jan 2015

    Assessment of knee joint pain in experimental rodent models of osteoarthritis.

    • Margaret J Piel, Jeffrey S Kroin, and Hee-Jeong Im.
    • Comparative Medicine Consultants, Chicago, IL, 60631, USA.
    • Methods Mol. Biol. 2015 Jan 1;1226:175-81.

    AbstractPain assessment in animal models of osteoarthritis is integral to interpretation of a model's utility in representing the clinical condition, and enabling accurate translational medicine. Here we describe two methods for behavioral pain assessments available for use in animal models of experimental osteoarthritic pain: Von Frey filaments and spontaneous activity monitoring.

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