• G Mallarini and L Saba.
• Department of Radiology, University Hospital of Cagliari - Monserrato, Cagliari, Italy.
• Minerva Ginecol. 2010 Dec 1;62(6):541-9.

AimThe prevalence of infertility in the United States is 15-20% and this condition represents an important medical problem. The purpose of this work was to evaluate therapeutical efficacy of 2 consecutive hysterosalpingography (HSG) followed each other after 4 week compared with the fallopian tube recanalization (FTR).MethodsTwo groups of 80 patients paired for mean age and age range (age range, 23-37 years; mean age, 30 years), were assessed for pregnancy rate (two-year follow-up) by using two consecutive HSG in one group and HSG and tube recanalization in the second group. Pain perception and dose delivered were assessed. Statistical analysis was performed to evaluate significant differences between the two approaches.ResultsPregnancy rate after TFR was 51% whereas pregnancy rate after two consecutive HSG was 31.3% (P= 0.016; OR 2.31) and all the pregnancies were observed in those women that showed a positive variation in second HSG with a pregnancy rate of 47% (P=0.776; OR=1.18). In one case a serious complication was observed (1.25%): a tubal perforation. Minor bleeding sometimes lasted for as long as 48 h but never required any medical treatment. Pain assessment and dose delivered were statistically different by using these two methods (P= 0.027 and P<0.001, respectively)ConclusionTherapeutical efficacy of two consecutive HSG followed each other after four week compared with the FTR are similar when the second HSG shows the presence of Fallopian tube patency.

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