• Luiz A Benvenuti, Francisco O S França, Kátia C Barbaro, José R Nunes, and João L C Cardoso.
• Laboratory of Pathology, Heart Institute (InCor), University of Sao Paulo Medical School, Av. Dr Enéas de Carvalho Aguiar 44, São Paulo, SP 05403-000, Brazil. anpluiz@incor.usp.br
• Toxicon. 2003 Sep 1;42(3):331-4.

AbstractA 36-year old woman was bitten on the left ankle by a Bothrops jararacussu, and died 45 min after the bite. At necropsy, there were local signs of envenoming with haemorrhage, thrombosis and necrosis of the subcutaneous and muscular tissue. Multiple fibrin and platelet thrombi were found in the microcirculation of the heart and lungs, suggesting the occurrence of disseminated intravascular coagulation. Pulmonary haemorrhage probably secondary to the action of haemorrhagins, consumption coagulopathy and disseminated intravascular coagulation was the immediate cause of death. Intravenous inoculation of the venom could have occurred in the present case, which would explain the rapid onset of coagulation disorders, haemorrhage and death.

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