• Medicina intensiva · Jan 2012

    [Influence of diurnal variation in the size of acute myocardial infarction].

    • E Arroyo Úcar, A Dominguez-Rodriguez, and P Abreu-Gonzalez.
    • Servicio de Cardiología, Hospital Universitario de Canarias, Tenerife, España.
    • Med Intensiva. 2012 Jan 1;36(1):11-4.

    ObjectiveTo evaluate whether the size of acute myocardial infarction (AMI) shows circadian variability.DesignAn observational, prospective study.SettingA 12-bed coronary care unit.PatientsConsecutive patients diagnosed with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention.InterventionsThe patients were divided into two groups according to the time of onset of AMI symptoms (Group A: 0-12hours, Group B: 12-24hours).Main Variables Of InterestAge, sex, cardiovascular risk factors, coronary anatomy, left ventricular ejection fraction, infarct location, time from onset of symptoms to reperfusion, presence of heart failure upon admission, and peak troponin I value.ResultsA total of 108 patients with a diagnosis of STEMI were included. Patients in group A showed a higher troponin I concentration compared to group B (troponin I: 70.85±16.38 versus 60.90±22.92ng / ml, p=0.003). In the multivariate analysis the onset of AMI between 0-12hours was identified as an independent predictor of infarct size (OR: 1.133, 95%CI 1.012-1.267, p=0.01).ConclusionsAn onset of AMI between 0-12hours results in a significantly larger final size of necrosis compared with any other time of presentation.Copyright © 2011 Elsevier España, S.L. and SEMICYUC. All rights reserved.

      Pubmed     Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…