• Resp Care · Oct 2011

    Case Reports

    Rhodococcus equi infection after lung transplantation.

    • Don Hayes, Enrique Diaz-Guzman, and Charles W Hoopes.
    • Departments of Pediatrics, Internal Medicine, and Surgery; University of Kentucky Medical Center; Lexington, Kentucky, USA. don.hayes@uky.edu
    • Resp Care. 2011 Oct 1; 56 (10): 1605-7.

    AbstractRhodococcus equi is an emerging opportunistic pathogen in immunocompromised patients. A lung-transplant recipient developed weight loss, nonproductive cough, dyspnea, and somnolence. Computed tomogram showed a pulmonary nodule and pleural changes in the right allograft that was due to R. equi infection. Alteration of cell-mediated immunity is a predisposing risk factor for R. equi infection in humans. Our patient developed R. equi infection soon after a course of high-dose corticosteroids for acute allograft infection and animal exposure. A course of intravenous vancomycin followed by single-agent long-term therapy with oral ciprofloxacin was successful.

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