• Ann Fr Anesth Reanim · Sep 2010

    Review

    [Coagulation disorders after traumatic brain injury: pathophysiology and therapeutic implications].

    • T Geeraerts, W Haïk, B Tremey, J Duranteau, and B Vigué.
    • Département d'anesthésie-réanimation chirurgicale, hôpital de Bicêtre, AP-HP, faculté de médecine, université Paris Sud, 78 rue du Général-Leclerc, Le-Kremlin-Bicêtre, France. geeraerts.t@chu-toulouse.fr
    • Ann Fr Anesth Reanim. 2010 Sep 1;29(9):e177-81.

    AbstractEarly activation of coagulation is common after traumatic brain injury. Its origin is probably mainly intracerebral, due to tissue factor release from the injured brain. Abnormalities in blood coagulation tests are associated with poor neurological prognosis. Coagulation activation may induce disseminated intravascular coagulation and fibrinolysis. Disseminated intravascular coagulation is linked to brain ischemia caused by intravascular microthrombosis. This review will focus on pathophysiology of coagulation disorders after traumatic brain injury, and on their implications for therapeutic approaches.Copyright (c) 2010 Elsevier Masson SAS. All rights reserved.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…