• Neurol. Sci. · Aug 2011

    Case Reports

    Relapsed spontaneous spinal epidural hematoma associated with aspirin and clopidogrel.

    • Seong Hoon Lim, Bo Young Hong, Ye Rim Cho, Han Seung Kim, Jong In Lee, Hye Won Kim, and Young Jin Ko.
    • Department of Rehabilitation Medicine, Seoul St. Mary Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
    • Neurol. Sci. 2011 Aug 1;32(4):687-9.

    AbstractAn acute spontaneous spinal epidural hematoma (SSEH) is a rare spinal pathology. A 57-year-old man who had hypertension and had been on dual antiplatelet therapy with aspirin and clopidogrel for primary prevention presented with the sudden onset of mid back pain and monoplegia of the left lower extremity. Magnetic resonance imaging revealed an epidural hematoma, and the patient underwent emergency hemilaminectomy for evacuation. However, the symptoms worsened, and complete paraplegia developed. A second procedure to remove the recurrent hematoma was performed. No vascular malformation or other possible cause for SSEH was found other than the aspirin and clopidogrel medication. This case report describes relapsed SSEH caused by the combination of aspirin and clopidogrel medication and urges caution in prescribing dual antiplatelet agents.

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