• Oral Surg Oral Med Oral Pathol Oral Radiol · Aug 2013

    Review

    Buprenorphine therapy: an increasing challenge in oral and maxillofacial surgery.

    • Michael Wasson and O Ross Beirne.
    • Department of Oral and Maxillofacial Surgery, University of Washington, Seattle, WA 98195-7134, USA.
    • Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 Aug 1;116(2):142-6.

    AbstractSuboxone is a 4:1 mixture of buprenorphine and naloxone and Subutex is buprenorphine alone. The high affinity μ-receptor binding of buprenorphine (Suboxone and Subutex) renders other opioids ineffective. Inadequate procedural sedation, inadequate analgesia, and significant drug interactions complicate the treatment of patients taking Suboxone or Subutex. Careful planning and an understanding of buprenorphine pharmacology can minimize potential perioperative complications in patients taking Suboxone or Subutex.Copyright © 2013. Published by Mosby, Inc.

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