• E S Li, P-Y Cheung, M O'Reilly, K Aziz, and G M Schmölzer.
• 1] Faculty of Science, McGill University, Montreal, QC, Canada [2] Neonatal Research Unit, Royal Alexandra Hospital, Edmonton, AB, Canada [3] Division of Neonatology, Department of Pediatrics, University of Alberta, Edmonton, AB, Canada.
• J Perinatol. 2015 Feb 1;35(2):142-5.

ObjectiveTo assess development of fatigue during chest compressions (CCs) in simulated neonatal cardiopulmonary resuscitation (CPR).Study DesignProspective randomized manikin crossover study. Thirty neonatal healthcare professionals who successfully completed the Neonatal Resuscitation Program performed CPR using (i) 3:1 compression:ventilation (C:V) ratio, (ii) continuous CC with asynchronous ventilation (CCaV) at a rate of 90 CC per min and (iii) CCaV at 120 CC per min for a duration of 10 min on a neonatal manikin. Changes in peak pressure (a surrogate of fatigue) and CC rate were continuously recorded and fatigue among groups was compared. Participants were blinded to pressure tracings and asked to rate their level of comfort and fatigue for each CPR trial.ResultCompared with baseline, a significant decrease in peak pressure was observed after 72, 96 and 156 s in group CCaV-120, CCaV-90 and 3:1 C:V, respectively. CC depth decreased by 50% within the first 3 min during CCaV-120, 30% during CCaV-90 and 20% during 3:1 C:V. Moreover, 3:1 C:V and CCaV were similarly preferred by healthcare professionals.ConclusionSimilarly, 3:1 C:V and CCaV CPR were also fatiguing. We recommend that rescuers should switch after every second cycle of heart rate assessment during neonatal CPR.

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