• M P Pai and F P Paloucek.
• Department of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago 60612, USA. apai@uic.edu
• Ann Pharmacother. 2000 Sep 1;34(9):1066-9.

ObjectiveTo provide a historical perspective on the origin and similarity of the "ideal" body weight (IBW) equations, and clarify the terms ideal and lean body weight (LBW).Data SourcesPrimary and review literature were identified using MEDLINE (1966-November 1999) and International Pharmaceutical Abstracts (1970-November 1999) pertaining to ideal and lean weight, height-weight tables, and obesity. In addition, textbooks and relevant reference lists were reviewed.Data ExtractionAll articles identified through the data sources were evaluated. Information deemed to be relevant to the objectives of the review were included.Data SynthesisHeight-weight tables were generated to provide a means of comparing a population with respect to their relative weight. The weight data were found to correlate with mortality and resulted in the use of the terms desirable or ideal to describe these weights. Over the years, IBW was interpreted to represent a "fat-free" weight and thus was used as a surrogate for LBW. In addition, the pharmacokinetics of certain drugs were found to correlate with IBW and resulted in the use of IBW equations published by Devine. These equations were consistent with an old rule that was developed from height-weight tables to estimate IBW. Efforts to improve the IBW equations through regression analyses of height-weight data resulted in equations similar to those published by Devine.ConclusionsThe similarity between the IBW equations was a result of the general agreement among the various height-weight tables from which they were derived. Therefore, any one of these equations may be used to estimate IBW.

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