• Mymensingh Med J · Jul 2009

    Randomized Controlled Trial Comparative Study

    Comparative efficacy of combined nebulized salbutamol with ipratropium bromide and nebulized adrenaline to treat children with acute bronchiolitis.

    • M A Kadir, A H Mollah, R Basak, A M Choudhury, and S Ahmed.
    • Pediatrics, Dhaka Medical College Hospital, Dhaka, Bangladesh. makadirped@gmail.com
    • Mymensingh Med J. 2009 Jul 1;18(2):208-14.

    AbstractAs the efficacy of combined nebulized salbutamol & ipratropium bromide as well as L-adrenaline to treat acute bronchiolitis is not well studied among the Bangladeshi infants, this study was carried out to see their efficacy in acute bronchiolitis and to compare their effectiveness. This randomized clinical trial was done among 60 children aged less than 02 years, admitted in the department of Pediatrics, Dhaka Medical College Hospital, during January through December 2005 with acute bronchiolitis. After a quick initial assessment, nebulization were done twice at 6 hours interval with the mentioned drugs, group wise (one group with salbutamol plus ipratropium bromide and other group with L-adrenaline alone) and the outcomes were assessed after 30 minutes of each nebulization in respect to oxygen saturation and clinical modified respiratory distress assessment instrument (MRDAI) scores. The results were analyzed by using SPSS version 10.0 and at a p value of

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