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Anaesth Intensive Care · Jan 2016
Letter Case ReportsAnaphylaxis to sugammadex diagnosed by skin prick testing using both sugammadex and a sugammadex-rocuronium mixture.
- T Nakanishi, K Ishida, K Utada, M Yamaguchi, and M Matsumoto.
- Yamaguchi, Japan.
- Anaesth Intensive Care. 2016 Jan 1; 44 (1): 122-4.
no abstract available
This article appears in the collection: Sugammadex anaphylaxis: all that glitters?.
Notes
Case report from Yamaguchi, Japan describing a confirmed sugammadex anaphylaxis in a 50kg woman receiving 4mg/kg sugammadex.
Notably, follow-up skin prick testing strongly suggests #1 hypersensitivity to free sugammadex molecules, rather than the sugammadex-rocuronium complex, and #2 hypersensitivity appears to be dose-related.
Daniel Jolley
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