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Conf Proc IEEE Eng Med Biol Soc · Jan 2008
Preliminary study on physiological changes of hemorrhagic shock in rats.
- Ju Hyung Lee, Soo Chan Kim, Tak Hyung Lee, Sang Won Chung, Hyung Wook No, and Deok Won Kim.
- Graduate Program in Biomedical Engineering, Yonsei University, Seoul, Korea. ssziq33@yuhs.ac
- Conf Proc IEEE Eng Med Biol Soc. 2008 Jan 1;2008:4891-4.
AbstractHemorrhagic shock is a common cause of death in emergency rooms. The objective evaluation of hemorrhagic shock is very important for early diagnosis and treatment. The purpose of this study is to understand its mechanism by analyzing the changes of bio-signals in hemorrhagic shock using controlled hemorrhage of Sprague-Dawley rats. We constructed an integrated system to be able to control bleeding and to simultaneously measure bio-signals such as ECG, blood pressure, temperature, and respiration. In order to verify the system, we measured the bio-signals mentioned above while hemorrhagic shock was induced by withdrawing blood (2.5 ml / 100 g / 15 min) from a femoral vein for 10 rats.
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