• British medical bulletin · Jan 1999

    Review

    Sedation and analgesia.

    • C Lerch and G R Park.
    • John Farman Intensive Care Unit, Addenbrooke's Hospital, Cambridge, UK.
    • Br. Med. Bull. 1999 Jan 1;55(1):76-95.

    AbstractSedation is a process of soothing. The concept of the ideal level of sedation is controversial and has changed over the last decade. A shift from deep sedation, often enhanced by muscle relaxants that completely detaches the patient from their environment, to light sedation rendering the patient sleepy but easily arousable has been widely accepted. This change in attitude has been brought about by sophisticated modes of ventilation allowing the ventilator to synchronize with the patient's own breathing pattern. In addition, the increasingly recognised adverse effects of over-sedation have contributed to the reduction in the depth of sedation.

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