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Randomized Controlled Trial
[The effects of preemptive dexketoprofen use on postoperative pain relief and tramadol consumption].
- Inci Kara, Sema Tuncer, Atilla Erol, and Ruhiye Reisli.
- Konya Training and Research Hospital, Konya, Turkey. drincikara@yahoo.com
- Agri. 2011 Jan 1;23(1):18-21.
ObjectivesIn this study, the efficacy of preemptive dexketoprofen usage on postoperative pain relief and tramadol consumption was evaluated.MethodsFifty American Society of Anesthesiologists (ASA)-I or ASA-II patients undergoing plastic surgery were randomized into two groups. Group 1 received dexketoprofen 25 mg and Group 2 received placebo tablets 1 hour (h) before surgery. All patients received a standard anesthetic protocol. At the end of the surgery, all patients received intravenous tramadol with Patient Controlled Analgesia (PCA) device. Pain scores was evaluated with visual analog scale during the postoperative 1st, 8th and 24th h. Tramadol consumption, adverse effects and patient satisfaction were recorded.ResultsThe pain scores and tramadol consumption were significantly lower in Group 1 (p<0.05). Nausea and vomiting were observed more in Group 2 than Group 1, and patient satisfaction was better in Group 1 (p<0.05).ConclusionPreemptive use of dexketoprofen reduced postoperative tramadol consumption and incidence of adverse events.
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