• Y Nakata, T Goto, H Saito, F Ichinose, S Uezono, K Suwa, and S Morita.
• Department of Anesthesia, Teikyo University School of Medicine and Ichihara Hospital, Chiba, Japan.
• J Clin Anesth. 1998 May 1;10(3):200-3.

Study ObjectivesTo compare acceleromyography (AMG) and electromyography (EMG) with xenon or sevoflurane anesthesia during vecuronium-induced neuromuscular blockade.DesignProspective randomized study.SettingUniversity hospital.Patients28 ASA physical status I and II adult patients presenting for elective surgery.InterventionsPatients received vecuronium for neuromuscular blockade and either xenon (n = 11) or sevoflurane (n = 17) anesthesia.Measurements And Main ResultsThe first twitch depression, which was expressed as a ratio of the first twitch to that obtained before the blocking drug was administered (T1/Tc), was measured simultaneously by AMG and EMG. T1/Tc as measured by AMG consistently demonstrated greater depression than that by EMG during recovery. The limits of agreement were unacceptably wide, suggesting that T1/Tc obtained by AMG is a poor predictor of T1/Tc as measured by EMG. Such relations were not affected by the anesthetic (xenon or sevoflurane) used.ConclusionAMG and EMG-cannot be used interchangeably with either xenon or sevoflurane anesthesia.

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