• Bull. Exp. Biol. Med. · Aug 2010

    Nuclear ploidy is an indicator of malignancy endocrine pancreatic tumor.

    • E A Dubova, M N Podgornova, and A I Shchyogolev.
    • Department of Pathological Anatomy, A. V. Vishnevsky Institute of Surgery, Moscow, Russia.
    • Bull. Exp. Biol. Med. 2010 Aug 1;149(2):236-8.

    AbstractComparative morphometric and densitometric studies of cell nuclei in endocrine tumors of various differentiation degree and endocrinocytes of Langerhans islet in the adjacent pancreatic tissue were carried out. Index of proliferative activity, aneuploidy coefficient, and histogram of nuclear DNA content are recommended as additional criteria for the diagnosis of endocrine tumor malignancy.

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