• Methods Mol. Biol. · Jan 2015

    Mechanical nociception measurement in mice and rats with automated Von Frey equipment.

    • Gabriele Campana and Roberto Rimondini.
    • Pharmacy and Biotechnology Department - FaBiT, University of Bologna, Bologna, Italy, gabriele.campana@unibo.it.
    • Methods Mol. Biol. 2015 Jan 1;1230:229-31.

    AbstractVon Frey hairs are important tools for the study of mechanisms of cutaneous stimulation-induced sensory input. Mechanical force is exerted via application of a particular hair to the cutaneous receptive field until buckling of the hair occurs. The most commonly used Von Frey filaments are productive in evaluating behavioral responses of neuropathic pain in preclinical and clinical research. To reduce the potential experimenter bias, automated instruments are being developed for behavioral assessment.

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