• Ann Fr Anesth Reanim · Jan 2010

    Case Reports

    [Successful use of recombinant factor VIIa in the control of a massive bleeding in two patients with biventricular assist device (Thoratec)].

    • N Fritsch, O Pouquet, B Roux, Y Abdelmoumen, and G Janvier.
    • Service de réanimation de chirurgie cardiaque, hôpital du Haut-Lévèque, CHU de Bordeaux, 1, avenue de Magellan, 33600 Pessac, France.
    • Ann Fr Anesth Reanim. 2010 Jan 1;29(1):45-7.

    AbstractMassive bleeding is a dreaded complication of biventricular mechanical assistance implantation. Its origin is multifactorial. Blood products transfusion associated with correction of coagulopathy are sometimes insufficient. We report two cases of massive bleeding after a Thoratec biventricular assistance implantation. After surgical haemostasis failure and despite the correction of coagulation disorders, a major bleeding persisted, so these patients received a single injection of 90 microg/kg of rFVIIa. This allowed in both cases a significant reduction of the bleeding and the restoration of normal haemodynamic conditions. This treatment was not complicated by any thrombotic accident.Copyright 2009. Published by Elsevier SAS.

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