• Comput. Biol. Med. · Oct 2013

    Evaluation of a novel automated non-invasive pulse pressure variation algorithm.

    • Martin Schmid, Helga Prettenthaler, Christian Weger, and Karl-Heinz Smolle.
    • Institute for Medical Engineering, University of Technology Graz, Austria.
    • Comput. Biol. Med. 2013 Oct 1;43(10):1583-9.

    AbstractIn mechanically ventilated patients, Pulse Pressure Variation (PPV) has been shown to be a useful parameter to guide fluid management. We evaluated a real-time automated PPV-algorithm by comparing it to manually calculated PPV-values. In 10 critically ill patients, blood pressure was measured invasively (IBP) and non-invasively (CNAP(®) Monitor, CNSystems Medizintechnik, Austria). PPV was determined manually and compared to automated PPV values: PPVmanIBP vs. PPVautoIBP was -0.19 ± 1.65% (mean bias ± standard deviation), PPVmanCNAP vs. PPVautoCNAP was -1.02 ± 2.03% and PPVautoCNAP vs. PPVmanIBP was -2.10 ± 3.14%, suggesting that the automated CNAP(®) PPV-algorithm works well on both blood pressure waveforms but needs further clinical evaluation.© 2013 Elsevier Ltd. All rights reserved.

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