• Saudi Med J · Oct 2007

    Randomized Controlled Trial

    Adding remifentanil to propofol and etomidate in cardioversion anesthesia.

    • Zeynep N Akcaboy, Erkan Y Akcaboy, Berrin Altinoren, Erdem Karabulut, and Nermin Gogus.
    • Department of Anesthesiology, The Ministry of Health Ankara Numune Research and Training Hospital, Ankara Numune Hastanesi, Ankara, Turkey. zakcaboy@yahoo.com
    • Saudi Med J. 2007 Oct 1;28(10):1550-4.

    ObjectiveTo compare their effects on cardiorespiratoy and recovery parameters and side effects.MethodsThis study was performed in The Ministry of Health Ankara Numune Research and Training Hospital, Ankara, Turkey, from January to May 2005. The 40 American Society of Anesthesiology II/III patients were randomized into 2 groups. All patients received remifentanil 0.75 microgram.kg(-1); and then received either etomidate 0.1 mg.kg(-1) (group E, n=20) or propofol 0.5 mg.kg(-1) (group P, n=20). Cardiorespiratory data, induction time, recovery parameters, pain scores, number of shocks (NS), total amount of energy used (TE), side effects, and patient/cardiologist satisfaction were recorded.ResultsInduction time and recovery parameters were shorter in group P. No differences were seen between the groups in NS and mean TE required. In group P, a statistically significant decrease in mean blood pressure occurred after induction and returned to its baseline levels in 6 minutes. After cardioversion over 2 minutes, the respiratory rates were decreased significantly more in group P when compared with group E. Two patients in group P became apneic and needed assisted ventilation. Pain scores, side effects and patient/cardiologist satisfaction were similar in both groups. No patients in either group had myoclonus.ConclusionWe can induce hypnosis with propofol 0.5 mg.kg(-1) or etomidate 0.1 mg.kg(-1) by adding remifentanil 0.75 microgram.kg-1 in cardioversion anesthesia. Although recovery parameters were longer in group E, and cardiorespiratory parameters were less stable in group P, their usage with remifentanil was both acceptable for cardioversion anesthesia.

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