• Stephanie H Wilson, Panayotis Fasseas, James L Orford, Ryan J Lennon, Terese Horlocker, Nina E Charnoff, Steven Melby, and Peter B Berger.
• Department of Cardiology, St. Vincent's Hospital, Darlinghurst, Australia.
• J. Am. Coll. Cardiol. 2003 Jul 16;42(2):234-40.

ObjectivesWe sought to determine the frequency and timing of complications at our institution when surgery was performed within two months of coronary stent placement.BackgroundThe optimal delay following coronary stent placement prior to non-cardiac surgery is unknown.MethodsWe analyzed the Mayo Clinic Percutaneous Coronary Intervention and Surgical databases between 1990 and 2000 and identified 207 patients who underwent surgery in the two months following successful coronary stent placement.ResultsEight patients (4.0%) died or suffered a myocardial infarction or stent thrombosis. All 8 patients were among the 168 patients (4.8%, 95% confidence interval [CI] 2.1 to 9.2) undergoing surgery six weeks after stent placement; the frequency of these events ranged from 3.8% to 7.1% per week during each of the six weeks. No events occurred in the 39 patients undergoing surgery seven to nine weeks after stent placement (0%, 95% CI 0.0 to 9.0).ConclusionsThese data suggest that, whenever possible, non-cardiac surgery should be delayed six weeks after stent placement, by which time stents are generally endothelialized, and a course of antiplatelet therapy to prevent stent thrombosis has been completed.

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