• Acta radiologica · Nov 2005

    Case Reports Comparative Study

    Transient splenial lesion of corpus callosum associated with antiepileptic drug: conventional and diffusion-weighted magnetic resonance images.

    • B Hakyemez, C Erdogan, N Yildirim, G Gokalp, and M Parlak.
    • Department of Radiology, Uludag University Medical School, Bursa, Turkey. bahattinh@hotmail.com
    • Acta Radiol. 2005 Nov 1;46(7):734-6.

    AbstractTransient focal lesions of splenium of corpus callosum can be seen as a component of many central nervous system diseases, including antiepileptic drug toxicity. The conventional magnetic resonance (MR) findings of the disease are characteristic and include ovoid lesions with high signal intensity at T2-weighted MRI. Limited information exists about the diffusion-weighted MRI characteristics of these lesions vanishing completely after a period of time. We examined the conventional, FLAIR, and diffusion-weighted MR images of a patient complaining of depressive mood and anxiety disorder after 1 year receiving antiepileptic medication.

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