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Ann Fr Anesth Reanim · May 2004
Case Reports[Increase in bispectral index induced by antihyperalgesic dose of ketamine].
- K Chaaben, E Marret, L Lamonerie, N Lembert, and F Bonnet.
- Département d'anesthésie-réanimation, 4, rue de la Chine, 75970 Paris cedex 020, France.
- Ann Fr Anesth Reanim. 2004 May 1;23(5):513-6.
AbstractWe report two cases of sudden increase in Bispectral Index (BIS) after the injection of low-dose ketamine for the prevention of postoperative hyperalgesia. The two patients were anaesthetised with a continuous infusion of remifentanil associated with propofol for one and isoflurane for the other. Changes in BIS occurred while the two patients were in a stable phase of surgery (beginning of parietal closure and suture of an anastomosis) and had a stable target concentration of anaesthetic agents. No others signs of awakening were observed. The BIS value returned progressively to 40-50 despite no increase in target concentration. None of the patients complained of intra-operative recall.
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