• Acta Neurol. Scand. · Feb 2002

    Clinical Trial

    Long-term intrathecal Baclofen infusion in supraspinal spasticity of adulthood.

    • A Dario, M G Di Stefano, A Grossi, F Casagrande, and G Bono.
    • Department of Neurosurgery, University of Insubria, Italy. dario.alessandro@virgilio.it
    • Acta Neurol. Scand. 2002 Feb 1;105(2):83-7.

    ObjectiveTo evaluate long-term results of chronic intrathecal Baclofen infusion on the spasticity, on the spasms and to evaluate the side-effects of the intrathecal Baclofen in patients with supraspinal spasticity.Clinical Materials And MethodsFourteen patients with severe progressive refractory to medical therapy spasticity were evaluated after chronic intrathecal Baclofen infusion performed by implantation of subcutaneous pump. The patients had suffered traumatic or anoxic acquired brain injuries. The clinical evaluation was made using Ashworth Scale (AS) and the Spasm Frequency Scale (SFS).ResultsThe intrathecal therapy showed a statistically significant improvement of the tone and of the spasms.ConclusionsThe intrathecal infusion of Baclofen seems to be an effective treatment in patients with supraspinal spasticity.

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