• A Giese, A Ornek, M Kurucay, L Kilic, S N Şendur, A Münker, C Puchstein, E Lainka, H Wittkowski, and B F Henning.
• Medizinische Klinik I, St. Josef-Hospital Bochum, Ruhr-Universität Bochum, Gudrunstr. 56, 44791, Bochum, Deutschland, arnd.giese@rub.de.
• Schmerz. 2013 Dec 1; 27 (6): 605-11.

BackgroundFamilial Mediterranean fever (FMF) is an autoinflammatory disease characterized by bouts of fever and serositis. Morbidity caused by bouts as well as self-medication were assessed among patients of Turkish ancestry living in Germany (D) or Turkey (T) in order to evaluate current analgetic concepts from a patient's perspective.Material And MethodsD and T were asked about the 3 months preceding the interview.ResultsA total of 40 D and 40 T were included; 35/40 D and 40/40 T were on colchicine. In the last 3 months, 61.3 % had ≥ 1 bout and suffered from peritonitis (87.8 %), fever (61.2 %), myalgia (45 %), pleuritis (42.8 %), arthralgia (36.7 %), and cephalgia (32.6 %). Of the patients, 65.3 % were bedridden during bouts, 61.2 % sought the attention of a physician, 53.1 % were unable to work or attend school, and 38.8 % were hospitalized. The following drugs were taken: NSAIDs (45.6 %), NSAIDs and paracetamol (42.6 %), and combinations of NSAIDs with other analgesics. NSAIDs (58.6 %) and paracetamol (20.7 %) were considered the most potent substances.ConclusionFMF inflicts substantial morbidity. Patients most commonly rely on NSAIDs and paracetamol to relieve symptoms of FMF bouts.

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