• J. Toxicol. Clin. Toxicol. · Jan 1996

    Review Case Reports

    Salicylism from topical salicylates: review of the literature.

    • J R Brubacher and R S Hoffman.
    • New York Poison Control Center, New York 10016, USA.
    • J. Toxicol. Clin. Toxicol. 1996 Jan 1;34(4):431-6.

    BackgroundAlthough topical salicylates are widely used, toxicity from this route is rare.Case ReportWe present an unusual case of salicylism from a topical salicylate preparation in an 80-year-old woman. The patient was admitted to the dermatology service with a diagnosis of erythroderma and was treated with salicylate containing ointments. After six days of treatment the patient became confused and paranoid. A serum salicylate was 3.36 mmol/L (46 mg/dL). The patient was admitted to the intensive care unit were she was rehydrated and treated with bicarbonate and activated charcoal.ResultsHer serum salicylate fell to 1.90 mmol/L (26 mg/dL) over a two day period and she regained a normal mental status.

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