• Ann Fr Anesth Reanim · Feb 2014

    Review

    Transcranial magnetic stimulation in brain injury.

    • E Castel-Lacanal, M Tarri, I Loubinoux, D Gasq, X de Boissezon, P Marque, and M Simonetta-Moreau.
    • Service de médecine physique et réadaptation, CHU Rangueil, 1, avenue Jean-Poulhès, TSA 50032, 31059 Toulouse cedex 9, France; Inserm U 825, CHU Purpan, pavillon Baudot, place du Dr-Baylac, 31024 Toulouse cedex 3, France. Electronic address: castel-lacanal.e@chu-toulouse.fr.
    • Ann Fr Anesth Reanim. 2014 Feb 1;33(2):83-7.

    ObjectivesTranscranial magnetic stimulations (TMS) have been used for many years as a diagnostic tool to explore changes in cortical excitability, and more recently as a tool for therapeutic neuromodulation. We are interested in their applications following brain injury: stroke, traumatic and anoxic brain injury.Data SynthesisFollowing brain injury, there is decreased cortical excitability and changes in interhemispheric interactions depending on the type, the severity, and the time-lapse between the injury and the treatment implemented. rTMS (repetitive TMS) is a therapeutic neuromodulation tool which restores the interhemispheric interactions following stroke by inhibiting the healthy cortex with frequencies ≤1Hz, or by exciting the lesioned cortex with frequencies between 3 and 50Hz. Results in motor recovery are promising and those in improving aphasia or visuospatial neglect are also encouraging. Finally, the use of TMS is mainly limited by the risk of seizure, and is therefore contraindicated for many patients.ConclusionTMS is a useful non-invasive brain stimulation tool to diagnose the effects of brain injury, to study the mechanisms of recovery and a non-invasive neuromodulation promising tool to influence the post-lesional recovery.Copyright © 2013 Société française d’anesthésie et de réanimation (Sfar). Published by Elsevier SAS. All rights reserved.

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