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Gen Thorac Cardiovasc Surg · Nov 2008
Case Reports Comparative StudyLevosimendan and severe pulmonary hypertension during open heart surgery.
- Ferit Cicekcioglu, Ali Ihsan Parlar, Ozgur Ersoy, Kerem Yay, Alaa Hijazi, and S Fehmi Katircioglu.
- Kalp ve Damar Cerrahisi Klinigi (Cardiovascular Surgery Clinic), Turkiye Yuksek Ihtisas Hastanesi, Sihhiye, Ankara 06100, Turkey.
- Gen Thorac Cardiovasc Surg. 2008 Nov 1;56(11):563-5.
AbstractWeaning from cardiopulmonary bypass is the most important stage during mitral valve surgery, especially in patients with severe pulmonary hypertension. We report two patients with severe pulmonary hypertension who were operated on because of valvular heart disease. To reduce the pulmonary artery pressure, levosimendan was used because of its vasodilatory and cytoprotective effects. All patients tolerated the operation and levosimendan administration. Their postoperative course was uneventful. Levosimendan can be used to treat pulmonary hypertension during operations for heart valve disease. Patients clearly benefit from the vasodilator action of the drug for reducing pulmonary artery pressure.
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