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- Alan D Kaye and Cara M Bevinetto.
- Department of Anesthesiology, University of Alabama School of Medicine, Birmingham, AL 35294, USA.
- J Clin Anesth. 2014 Feb 1;26(1):75-9.
AbstractAngelman syndrome arises by one of 4 genetic mechanisms. Patients often have craniofacial abnormalities, vagal hypertonia, skeletal muscle atrophy or underdevelopment, a history of seizure disorders, and pharmacodynamic unpredictability. Its pathogenesis, clinical manifestations, diagnosis and treatment options, and perioperative anesthetic considerations are presented.Copyright © 2014 Elsevier Inc. All rights reserved.
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