• Ann Fr Anesth Reanim · Mar 2014

    Case Reports

    [Prolonged phase II neuromuscular blockade following succinylcholine administration.]

    • G Jurkolow, T Fuchs-Buder, A Lemoine, J Raft, N Rocq, and C Meistelman.
    • Département d'anesthésie-réanimation, université de Lorraine, CHU de Nancy-Brabois, rue du Morvan, 54511 Vandœuvre-lès-Nancy, France. Electronic address: g.jurkolow@chu-nancy.fr.
    • Ann Fr Anesth Reanim. 2014 Mar 1;33(3):176-7.

    AbstractPatients who are given a single dose of succinylcholine normally undergo a short-acting depolarizing phase I neuromuscular block but rarely a phase II block. Prolonged neuromuscular blockade occurs after a single dose of succinylcholine in case of genetically determined abnormal plasma butyrylcholinesterase activity. It is mandatory to use monitoring to detect this side effect. We report a case of a patient with abnormal plasma butyrylcholinesterase activity undergoing a six-hour prolonged neuromuscular phase II block, after a single dose of succinylcholine.Copyright © 2014 Société française d’anesthésie et de réanimation (Sfar). Published by Elsevier SAS. All rights reserved.

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