• S McNeill, J C Gatenby, S McElroy, and B Engelhardt.
• Vanderbilt University Medical Center, Department of Pediatrics, Division of Neonatology, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN 37232–9544, USA.
• J Perinatol. 2011 Jan 1;31(1):51-7.

ObjectiveThe aim of this study is to characterize baseline regional oxygen saturations (rSO(2)) in stable preterm infants during the first weeks of life.Study DesignCerebral, renal and abdominal rSO(2) were continuously monitored from the time of birth to 21 days in twelve preterm infants of 29-34 weeks gestation. Regional saturations were evaluated for trends over time, variability and differences between gestational ages (GAs) and reported pediatric values.ResultBoth cerebral (66-83%) and renal (64-87%) rSO(2) baselines were within the range of reported neonatal values but consistently decreased over the first weeks of life (P<0.01). The baseline abdominal rSO(2) was 32-66% and increased with GA (P=0.05). The rSO(2) variability was lowest for cerebral measurements and highest at the abdomen. Abdominal rSO(2) variability decreased over time (P≤0.05).ConclusionDaily baseline rSO(2) in preterm infants changes over the first weeks of life, especially at the abdomen. Evolution in baseline rSO2 over time may indicate regional developmental maturation of physiological oxygen balance.

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