• Eugene W Moretti, Kerri M Robertson, J E Tuttle-Newhall, Pierre-Alain Clavien, and Tong-Joo Gan.
• Department of Anesthesiology, PO Box 3094, Duke University Medical Center, Durham, NC 27710, USA. moret002@mc.duke.edu
• J Clin Anesth. 2002 Sep 1;14(6):416-20.

Study ObjectiveTo compare postoperative morphine use, analgesic efficacy, and side effect profiles in patients following orthotopic liver transplantation (OLTx) and liver resection (LR).DesignRetrospective study.SettingLiver transplant and liver resection surgery at a university hospital.Patients25 ASA physical status I, II, III, and IV patients undergoing OLTx or liver resection.Measurements And Main ResultsMorphine use was significantly decreased in the OLTx patients at 6,12, 24, 48, and 72 hours following commencement of patient-controlled analgesia. After commencement of patient-controlled analgesia, pain scores were significantly reduced in the OLTx group compared with those in the liver resection group at 6 and 12 hours.ConclusionsOrthotopic liver transplant patients experienced less pain and used less morphine postoperatively than did liver resection patients.

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