• Preet Mohinder Singh, Anjan Trikha, Renu Sinha, and Anuradha Borle.
• Department of Anaesthesia, All India Institute of Medical Sciences, New Delhi, India.
• J Anaesthesiol Clin Pharmacol. 2013 Oct 1;29(4):516-20.

BackgroundThe most common drugs used in an operating room are the Inhalation agents for maintenance of anesthesia yet their measurement methods during the procedure are not well-validated. Conventional methods of measuring the vaporizer weight after each use suffers from practical limitations of high error and time constraints.AimsWe compared two alternative methods available (Dion's method and Drager Inc. patent protocol) for their degree of concordance and correlation in real-time consumption of sevoflurane for pediatric procedures.ResultsBoth methods showed a very strong correlation (0.895 [P > 0.001]). Dion's method underestimated consumption by 2.59 ml with limits of agreement between 5.188 ml and -0.008 ml. Both test results showed a strong correlation, but poor concordance.ConclusionsDion's method strongly correlates with Drager protocol although concordance between the two methods for measuring anesthetic gas consumption is poor. Dion's method underestimates the consumption and with slight modification addressing this underestimation, it can be electronically incorporated in other workstations to overcome limitations of real-time measurement of inhalation agent consumption.

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