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Randomized Controlled Trial Comparative Study Clinical Trial
Comparison of four local extradural anaesthetic solutions for elective caesarean section.
- P Howell, W Davies, M Wrigley, P Tan, and B Morgan.
- Queen Charlotte's and Chelsea Hospital, London.
- Br J Anaesth. 1990 Nov 1;65(5):648-53.
AbstractWe have examined a combination of two local anaesthetics to see if the resultant solution is superior to the agents individually. This study shows that a mixture of bupivacaine and lignocaine provided an excellent alternative to bupivacaine alone, and was superior to 2% lignocaine with adrenaline for elective Caesarean section. By reducing the dose of bupivacaine used, the combination may reduce the risk of cardiotoxicity.
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