• Br J Anaesth · Nov 1990

    Randomized Controlled Trial Comparative Study Clinical Trial

    Comparison of four local extradural anaesthetic solutions for elective caesarean section.

    • P Howell, W Davies, M Wrigley, P Tan, and B Morgan.
    • Queen Charlotte's and Chelsea Hospital, London.
    • Br J Anaesth. 1990 Nov 1;65(5):648-53.

    AbstractWe have examined a combination of two local anaesthetics to see if the resultant solution is superior to the agents individually. This study shows that a mixture of bupivacaine and lignocaine provided an excellent alternative to bupivacaine alone, and was superior to 2% lignocaine with adrenaline for elective Caesarean section. By reducing the dose of bupivacaine used, the combination may reduce the risk of cardiotoxicity.

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