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Ann Fr Anesth Reanim · Jul 2009
Case Reports[Severe differed respiratory depression after intrathecal administration of morphine and clonidine on a 70-year-old patient].
- A F Ouro-Bang'na Maman, H D Sama, F Alassani, P Egbohou, and M Chobli.
- Service d'Anesthésie Réanimation, CHU de Lomé, Université de Lomé, Agbalépédogan, Lomé, Togo.
- Ann Fr Anesth Reanim. 2009 Jul 1;28(7-8):701-3.
AbstractWe report a case of severe and differed respiratory depression to a 70-year-old patient after spinal anaesthesia for prostatic adenomectomy. Ten milligram of bupivacaine, 30 microg of clonidine and 100 microg of morphine has been administrated intrathecally. The anaesthesia has lasted 4h and, 16h after the induction, the patient had a respiratory depression with bradypnea (5c/min), hypoxia (SpO(2) 80%) and sedation (scale 3 of Wilson). The evolution was favourable after intravenous injection of naloxone and oxygenotherapy. The use of low dose intrathecal morphine can involve a respiratory depression. Intrathecal association of morphine and clonidine must be careful used among old patients and require a monitoring during the first 24h.
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