-
- J Van Hoff, A K Ritchey, and B A Shaywitz.
- Am. J. Dis. Child. 1985 Nov 1;139(11):1120-3.
AbstractWe treated two children with sickle cell disease and intracranial hemorrhage. The incidence of intracranial hemorrhage is increased in sickle cell disease, although not as markedly as that of cerebral infarction. Intracranial hemorrhage has a higher mortality, a lower rate of permanent neurologic impairment, and occurs more often in older patients than does cerebral infarction. Intracranial hemorrhage in adults is likely to be an intracerebral hemorrhage or a subarachnoid hemorrhage secondary to an aneurysm. Children, however, are more likely to have subarachnoid hemorrhage without an identifiable aneurysm. We hypothesize that both hemorrhages and infarcts are due to large-vessel cerebral vasculopathy secondary to the abnormal rheologic features of sickled cells.
Notes
Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes
- Simple formatting can be added to notes, such as
*italics*,_underline_or**bold**. - Superscript can be denoted by
<sup>text</sup>and subscript<sub>text</sub>. - Numbered or bulleted lists can be created using either numbered lines
1. 2. 3., hyphens-or asterisks*. - Links can be included with:
[my link to pubmed](http://pubmed.com) - Images can be included with:
 - For footnotes use
[^1](This is a footnote.)inline. - Or use an inline reference
[^1]to refer to a longer footnote elseweher in the document[^1]: This is a long footnote..