• Mosavir Ansarie, Asif Naseem, Aneeka Kasmani, Rasheed Ahmed, and Muhammad Azeemuddin.
• Chest. 2014 Mar 1;145(3 Suppl):241A.

Session TitleILD PostersSESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: No published data is available to provide any information about the status of Interstitial Lung Diseases (ILD) in Pakistan. However this study is in continuation of presented data from 2008-11 (Ansarie et al, ERS 2012) to determine the ongoing incidence and relative frequency of various ILDs in Karachi, it's most populous multiethnic city (20 million).MethodsWe reviewed data from a registry catering to 4 pulmonology clinics in different areas of the city. The registry is based on a detailed questionnaire in which age, gender, exposure history, clinical presentation, HRCT and PFT findings are mandatorily recorded and also BAL, VATS & histopathology data if available. It prospectively recorded diagnosed ILD cases between January 2012 to August 2013.ResultsIn a total of 2065 pulmonology referrals during this registry period, the incidence of ILD was 5.1% (n=106) with a mean age of 55.9 years (±12.9 SD). Out of 106 ILD cases; Idiopathic Pulmonary Fibrosis (IPF) (33%), Non Specific Interstitial Pneumonitis (NSIP) (27.4%) and Sarcoidosis (19.8%) were the most frequent ILDs followed by Hypersensitivity Pneumonitis (HP) (9.4%), Collagen Vascular Disease Related (4.7%) and others (5.7%). Reporting females (n=70) outnumbered males (n=36). The incidence of IPF was significantly greater in males (47.2%; p=0.026) and NSIP occurred significantly more in females (34.3%; p=0.027) while the difference in incidence of sarcoidosis between the two sexes was insignificant (males 19.4% vs. females 20%; p=0.959). Interestingly, out of 18 IPF & 5 HP diagnosed housewives living in congested areas, 44.4% & 40% respectively had avian exposure due to home breeding/pets.ConclusionsThis ongoing registry establishes for the first time a rising incidence of ILD in Pakistani population and describes its diagnostic facets.Clinical ImplicationsWe hope that this will lead to greater disease awareness and help us in expanding this registry to all major cities of Pakistan.DisclosureThe following authors have nothing to disclose: Mosavir Ansarie, Asif Naseem, Aneeka Kasmani, Rasheed Ahmed, Muhammad AzeemuddinNo Product/Research Disclosure Information.

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