• Chest · Mar 2014

    Lung resections for primary malignancies in patients younger than 40 years: a review of cases in a fifteen year period.

    • David Gomez, Daniel Valdivia, Lidia Macias, and Lucas Hoyos.
    • Chest. 2014 Mar 1;145(3 Suppl):329A.

    Session TitleLung Cancer Posters IISESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: Review the characteristics and outcomes of patients in our seriesMethodsRetrospective analysis of patients younger than 40 years undergoing lung resection for primary malignant tumors in our department between 1997-2012.ResultsN = 24. 16 (67.7%) men. Average age: 32.7 years (range 13-40 years). 12 (50%) patients were smokers. The most common comorbidity was hypertension 17%. The histologic types were: Adenocarcinoma 8 (33.3%), Typical Carcinoid 8 (33.3%), Mucoepidermoid 3 (12.5%), Squamous Cell Carcinoma 2 (8.3%), Neuroendocrine 1 (4.2%), Large Cell Carcinoma 1 (4.2%) and Germ Cell Carcinoma of Pulmonary Origin 1 (4.2%). Procedures performed: 16 lobectomies (15 by open approach and one by VATS) and of these three were made with bronchoplasty, one with chest wall resection and one with diaphragm resection. 2 segmentectomies, one atypical and one typical (lingulectomy), 3 pneumonectomies and 2 sleeve resections without associated lobectomy. In 1 case a bilobectomy was performed. The median stay was 6.5 days (range 4-28). The incidence of postoperative complications was 35% (pleural effusion 3 cases (15%), fever 2 cases (10%), oxygen therapy, atelectasis and vocal cord paralysis one case each (5%)). The survival for each stage at 1, 3 and 5 years respectively was: IA: 100% in the 3 evaluation periods, IB: 100, 100, and 80%, II A: 100, 75 and 75%, II B: 100, 100 and 50%, III A 100, 0 and 0%. A patient with stage IV died 4 years after surgery. Patient with Germ Cell Carcinoma of Pulmonary Origin had a completed pathological response after induction chemotherapy. No patient died during hospitalization or in the first year after surgery.ConclusionsAdenocarcinoma and Typical Carcinoid are the most common histological types in our series. Early diagnosis and complete resection helps to improve survival in these patients.Clinical ImplicationsProvide data on a group of patients where the lung cancer remains rareDisclosureThe following authors have nothing to disclose: Daniel Valdivia, Lucas Hoyos, Lidia Macias, David Gomez, Andres VarelaNo Product/Research Disclosure Information.

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