• Marie Carmen Valenza, Irene Torres-Sánchez, Gerald Valenza-Demet, Irene Cabrera-Martos, and Angela Ruiz-Saez.
• Chest. 2014 Mar 1;145(3 Suppl):384A.

Session TitleCOPD PostersSESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: Acute exacerbations (AEs) have a negative impact on various aspects of the progression of COPD, but objective and detailed data on the impact of hospitalizations for an AE are needed. This study was designed to evaluate the effects of hospitalization on multiple functional parameters in adults with acute exacerbation of COPD.MethodsWe aimed to investigate the repercussion of hospitalization on pulmonary function (spirometry), dyspnea (modified Borg scale), anxiety and depression (Hospital Anxiety and Depression questionnaire, HAD ) and independence (Barthel index). 66 COPD patients (mean age, 75.87 years [6.14 SD]; body mass index, 26.46 kg/m2 [6.49 SD]) at the beginning and end of a hospitalization period for an AE.ResultsMean differences on pulmonary function parameters were -0.17 ± 0.705 [-0.419 , 0.073] p=1.62 for FVC (mean ±SD [CI 95%]) and -0.02 ± 0.323 [-0.135 , 0.089], p=0.682 for FEV1 when compared before and after hospitalization showing little improvements in pulmonary function. Dyspnea scores improves significantly mean change 2.87 ± 1.984 [2.280 , 3.459] p<0.001. Anxiety and depression scores shows worse values after the hospitalization period, mean change: -1.00 ± 5.646 [-2.41 , 0.410] p=0.161. No differences were found between independence values at admission and at discharge.ConclusionsIn this group of COPD older adults the hospitalization period resulted in worse values of anxiety and depression, while no significant differences were found in pulmonary function parameters. Yet there was no change in independence values.Clinical ImplicationsFunctional repercussion of hospitalization need to be taken into account in the care of this kind of patients.DisclosureThe following authors have nothing to disclose: Marie Carmen Valenza, Maria José Flores-Barba, Gerald Valenza-Demet, Irene Torres-Sánchez, Irene Cabrera-Martos, Angela Ruiz-SaezNo Product/Research Disclosure Information.

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