• Doina Adina Todea, Paraschiva Postolache, Loredana Elena Rosca, and Andreea Codruta Coman.
• Chest. 2014 Mar 1;145(3 Suppl):576A.

Session TitleComorbidities of OSA PostersSESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: Type 2 diabetes mellitus (DM) and obstructive sleep apnea (OSA) share clinical outcomes being in this way a major public health concern. OSA may be under-recognised comorbidity of DM, so recent reports have indicated that the majority of patients with type 2 diabetes also have obstructive sleep apnea syndrome (OSA). The aim of the study was to evaluate the presence of diabetes mellitus between patients with obstructive sleep apnea syndrome.MethodsWe examined 151 patients diagnosed to our Sleep Laboratory Center, between January to December 2012, with OSA by nocturnal cardio-respiratory poligraphy (apnea hypopnea index - AHI, oxygen saturation - SpO2, lowest SpO2, oxygen desaturation index - ODI being registered) and we screened all this patients for type 2 diabetes mellitus. Including criteria was cut-off value of ≥15 events/h according to the Apnea Hypopnea Index.ResultsNinety-nine patients (65.56%) had severe OSAS (≥30 events/h); 100 patients (66.22%) had type 2 diabetes mellitus (62 males, 38 females). The average of: apnea hypopnea index was 43.85±16.84; SpO2 average was 91.57±3.17; ODI was 36.75±10.85; lowest SpO2 was 74.20±13.82; body mass index was 36.41±7.26. Receiver operating characteristics (ROC) analysis reveals statistic significance for: age (p<0.01,AUC=0.69), neck circumference (p<0.01, AUC=0.67), abdominal circumference (p<0.01,AUC=0.70),BMI (p<0.01,AUC=0.70), glicemia (p=0.03,AUC=0.59), medium O2 saturation (p<0.01, AUC=0.70),oxigen desaturation index (p<0.01, AUC=0.63) and ESS (p=0.03, AUC=0.5). We found a statistically significant association between diabetes mellitus and OSA severity (p=0.037).ConclusionsType 2 diabetes mellitus is frequent between patients with obstructive sleep apnea, especially in moderate and severe forms of OSA.Clinical ImplicationsBidirectional relationship will be appropriate in clinical practice so, patients with type 2 diabetes mellitus should be screened for OSA and patients with OSA should also be evaluated for type 2 diabetes mellitus.DisclosureThe following authors have nothing to disclose: Doina Adina Todea, Paraschiva Postolache, Andreea Codruta Coman, Loredana Elena RoscaNo Product/Research Disclosure Information.

16 keywords...

hide…